HORDB

ID: hor003986
Uniprot ID: Q5TV14
Protein name: Pyrokinin-1
Gene name: CAPA
Organism: Anopheles gambiae (African malaria mosquito)
Family: Pyrokinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: gambiae species complex, Pyretophorus, Cellia (subgenus), Anopheles (genus), Anophelinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: AGGTGANSAMWFGPRL
Length: 16(134-149)
Propeptide: MLAGSQAKPPVCVALALVLLGVTVHLAGAEAPEFESVGRVSKRGPTVGLFAFPRVGRSDPELNLDWESSAMLPLETADDYEDYPMKEMKRQGLVPFPRVGRSGKSELAMAAARYWQAARNLQQQQQQQSVVKRAGGTGANSAMWFGPRLGKRSRFGAAAASGSSEQQQQLKAEQL
Signal peptide: MLAGSQAKPPVCVALALVLLGVTVHLAGA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor003986_AF2.pdb

hor003986_ESM.pdb

Mass:	186053	Formula:	C70H105N21O20S
Absent amino acids:	CDEHIKQVY	Common amino acids:	G
pI:	10.55	Basic residues:	1
Polar residues:	7	Hydrophobic residues:	6
Hydrophobicity:	1.88	Boman Index:	-576
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.13
Instability Index:	-410.63	Extinction Coefficient cystines:	5500
Absorbance 280nm:	366.67

PubMed ID: 17709098
Title: Identification of One Capa and Two Pyrokinin Receptors From the Malaria Mosquito Anopheles Gambiae